ABSTRACT
Fetal echocardiography can be performed as early as the 16th week gestation and with improved equipment all forms of congenital heart diseases can be detected in utero. In this article we discuss the indications for a fetal heart echocardiography and the techniques used in a fetal heart examination and review the structural and functional information that can be obtained.
Subject(s)
Humans , Female , Pregnancy , Ultrasonography, Doppler , Heart Diseases/congenital , Heart Diseases , Risk FactorsABSTRACT
The authors studied two groups of natural animal reservoirs for Trypanosoma cruzi: a wild one, the common rat Rattus rattus and the house dog, Canis canis. Thirty one naturally infected rats were evaluated with a technique developed by the authors which allows the recording of the ECG and the performance of a ventricular angiogram without altering the functional capacity of the animal. Forty four dogs were followed clinically for a period of twenty years to study the development of the cardiac lesion seen in the chronic phase of the disease. The authors demonstrate the epidemiologic importance of the dog as a reservoir and the ease with which the infection can be acquired from rats, which live in the same habitat with human patients. The most common lesions in both groups were ventricular and atrial arrhythmias and second degree AV block; and, in the dogs, also death due to refractory cardiac failure, such as is seen in the human patient. Right bundle branch block and dilatation of the right cardiac chambers was the rule in both groups. The authors discuss the pathogenesis of the ECG in the rat and its anatomical basis. They propose the possibility of establishing and standardizing this techniques in the laboratories that study rats or other species
Subject(s)
Animals , Male , Female , Dogs , Dog Diseases/diagnosis , Chagas Cardiomyopathy/veterinary , Disease Reservoirs , Angiography/veterinary , Dog Diseases , Electrocardiography/veterinary , Chagas Cardiomyopathy/diagnosis , Chagas Cardiomyopathy , Muridae , Panama , RatsABSTRACT
Arterial hypertension is the main cause of cardiovascular problems in adults. To better know the scope of arterial hypertension in children in our midst, the authors measured the arterial blood pressure in 8642 Panamanian children between 1 month and 18 years of age and studied the principal causes of arterial hypertension. The authors propose norms for the identification and clinical and pharmacological management of arterial hypertension in Panamanian children
Subject(s)
Humans , Male , Female , Infant , Child, Preschool , Child , Adolescent , Arterial Pressure , Hypertension/diagnosis , Reference ValuesABSTRACT
The authors evaluated the serological response of metronidazole, or 8823 RP-(Hydroxy-2' ethy1)-1-methyl-2 nitro-5 imidazole) in 1307 patients, with Chagas' disease in the acute or chronic stage with age ranging between 6 months to 73 years. 273 patients were in the acute phase: 153 children and 120 adults. Patients in the chronic stage were classified with serological, clinical and cardiological criteria: 1.-POSITIVE SEROLOGY without cardiological signs or symptomatology (EKG, VECTO, ECHO M mode and 2-D, Chest Rx, physiological and pharmacological tests, radiocardiological-HMIBI, MUGA); 2.- POSITIVE SEROLOGY with cardiological signs and symptoms (all cardiological tests were abnormals); 3.- POSITIVE SEROLOGY with cardiomyopathy and cardiac failure. Metronidazole, P.O. or I.V. was utilizing dosages ranging from 15 to 25 mg/Kilo body weight per five days in acute phase and 250 to 500 mg. P.O. in the chronic stage of the disease for 180 days. The drug was well tolerated by all patients in both phases of the disease. Adequate anabolic effect was identified in both stages of the illness. Serological reactions were negative in all patients (100%) without cardiomyopathy. In patients with cardiomyopathy and cardiac failure, the complement fixation test title were similar before and after treatment
Subject(s)
Humans , Animals , Male , Female , Infant , Child, Preschool , Child , Adolescent , Adult , Middle Aged , Chagas Disease/drug therapy , Metronidazole/therapeutic use , Antibodies, Protozoan/blood , Drug Evaluation , Acute Disease , Chronic Disease , Chagas Disease/immunology , Panama , Trypanosoma cruzi/immunologyABSTRACT
The clinical record of 5 patients are studied. They were hospitalized in Santo Tomás Hospital with history of chronic and massive intoxication with inhaled and ingested cocaine. They all had cardiomegaly: in one, of grade I; in three, of grade III. The echocardiography mode B showed global cardiomegaly with dilatation of cavities and ejection fraction of 20% or below